Nomenclature of the Oxford classification of IgA nephropathy: do we need to be careful?

Validating the oxford classification of IgA nephropathy.

The evolution of patients with IgA nephropathy (IgAN) varies greatly, and predictive tools are needed to assess confidently the risk for progression. Although in many studies clinical risk factors such as hypertension and proteinuria have consistently been linked to outcome, the independent value of pathology remains debated. Pathologists have developed a number of classifications over the year...

The Oxford classification of IgA nephropathy: single centre experience.

The Oxford classification for the pathological classification of a glomerular disease in IgA nephropathy was established and published in 2009. Four of the pathological variables: 1) mesangial hypercellularity score, 2) segmental glomerulosclerosis, 3) endocapillary hypercellularity and 4) tubular atrophy/interstital fibrosis were presented as having value in predicting renal outcome in this gl...

The new Oxford Clinico-Pathological Classification of IgA nephropathy.

The new Oxford Classification of the Pathology of IgA nephropathy originated from an international collaborative effort of the Working Group of the International IgA Nephropathy Network and Renal Pathology Society. It provides a new common language to categorizing glomerular and tubulo-interstitial lesions in IgA nephropathy having a proved effect on progression. Although retrospective in desig...

Do Antibiotic Beads Need to be Removed?

Background: Polymethylmethacrylate antibiotic impregnated beads can be an effective treatment for chronicosteomyelitis or an adjuvant in the treatment of open fractures. It remains unclear however whether the beads causelong-term adverse events if not removed. The purpose of this study was to determine if removal of antibiotic beads wasrequired in order to avoid long term comp...

Prescribing of NSAIDs and ASA during pregnancy; do we need to be more careful?